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Drug FormulationA short article on the subject of drug formulation, formulation and drug stability, giving short examples. The process in which various drugs are brought together, to manufacture a medicinal product is known as Drug formulation. The formulation process inspects and then gives importance to factors such as the pH, polymorphism, solubility and particle size as all these can affect the actions of the drug. The drug formulation process needs to be continued until it reaches the last stages of clinical trials so that it can be used in the open market. However, this requires a good amount of knowledge regarding drug stability to be able to confirm that the drug is stable at the time of preparation. This is because if the drug is highly unstable then it will heavily invalidate the outcomes of the clinical trials, as it will be not possible to know the actual administered dose. The drug stability tests are carried to check the effect of factors such as weather temperature, photolysis, oxidation, humidity, visible light or UV light on the drug. Then the analysis of preparation of the drug is done to check whether any degraded products have formed. Special importance also needs to be given to any unusual reactions taking place between the container and the preparation to check for the presence of lubricants and plasticizers in the drug. Drug formulation process takes the form of oral formulations and topical medication forms Oral Formulations: These mainly include the formulation of drugs into the tablet form and capsule form. A tablet is a compressed preparation mainly consisting of the actual drug (5-10%) disintegrants, binders, fillers, glidants, lubricants (80%) and 10% of compounds that ensure easy disaggregation and disintegration of the tablet in the intestine or stomach. In a capsule, the main active substance is enclosed with a gelatinous envelope. It is designed in such a way so that the active component can remain intact for some amount of time after ingesting and to delay the process of absorption. Topical medication forms: These mainly include creams, gels, ointments Article Tags: Drug Formulation, Formulation Process Source: Free Articles from ArticlesFactory.com
ABOUT THE AUTHORArticle by Nadia at INTER-DEV SEO Company on behalf of Docoop Drug delivery systems
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