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lotensin-a general overview

Lotensin, is a drug used in hypertension, CCF, and chronic kidney failure.It may be used alone or in combination with thiazide diuretics.

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What it Lotensin?

 Lotensin, is a drug used in hypertension, CCF, and chronic kidney failure.

It may be used alone or in combination with thiazide diuretics.

Composition of lotensin

benazeperil

how it works?

 Upon breakage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.

Dose

The National Drug Codes for the various packages are

 

Tablets

 

Dose     Color    Bottle of 100

 

5 mg      light yellow    NDC 0078-0447-05

10 mg    dark yellow    NDC 0078-0448-05

20 mg    pink               NDC 0078-0449-05

40 mg    dark rose       NDC 0078-0450-05

Storage:

Do not store above 30°C (86°F).

 Protect from moisture

Oral

Lotensil is Available as tablets in strength of 5 mg, 10 mg, 20 mg, and 40 mg.

Benazepril is also available in combination with hydrochlorothiazide,  and with amlodipine under different brand names.

Side effects of lotensin

The Most common side effects of lotensin include headache and cough.

Rare side effects like Anaphylaxis and angioedema can also occur.

 Hyperkalemia, which is elevation of serum or say blood potassium levels, can also occur.

Benazepril may cause harm to the fetus during pregnancy. Hence it should be avoided during pregnancy.

Hpotension-on drug over dose may occur.. in case of over dose consult you doctor immediately,it is characterized by headache dizziness or patient may faint.

 

Contraindications

Benazepril should be discontinued during pregnancy.

If you are already taking Lotensin as your anti hypertensive medication,you need to stop when conceived, or better consult your doctor before you plan to conceive.

Lotensin should be discontinued during any planned surgery. If you are undergoing any surgery, inform your doctor before hand.

History of angioedema previously by use of other ACE inhibitors.

 

Lotensin use during Kidney disease

 Patients with advanced renal insufficiency taking Lotensin showed "substantial" kidney benefits.

A long term study of patients' kidney disease revealed that patients who took Lotensin had better kidney function and a slower progression of kidney disease. Kidney function was much better in the group of patients taking the drug than their peers who took a placebo drug. This is notable because this category of pharmaceuticals have long been thought to cause further kidney damage or increase the rate of progression for kidney disease.

According to coverage of the study on WebMD:

ACE inhibitors can pose a potential threat to kidneys as well. The key question was whether damaged kidneys would worsen if patients took ACE inhibitors. In a nutshell, concerns centered on blood levels of potassium and creatinine, waste products that are excreted by the kidneys. Testing creatinine levels in the blood is used as a way to monitor kidney function (...) kidney problems worsened more slowly in those taking Lotensin. Overall, there were no major differences in side effects between patients taking Lotensin or the placebo.

This study marks the first indication that lotensin, and perhaps other ACE inhibitors, may actually be beneficial in the treatment of hypertension in patients with kidney disease.

Veterinary use

 Benazepril hydrochloride is used to treat congestive heart failure in dogs and chronic renal failure in dogs and cats under different brand names.

 

Manufactured by:

Novartis Pharmaceuticals Corporation

Suffern, New York 10901

Distributed by:

Novartis Pharmaceuticals Corporation

East HanoverFree Web Content, New Jersey 07936

 

You can buy Lotensin online http://www.meds-hut.com/generic/blood-pressure/Lotensin.shtml

Source: Free Articles from ArticlesFactory.com

ABOUT THE AUTHOR


Hi, this is Kevin from www.meds-hut.com  , We do not offer any prescription for your medication. Buy only the medicines that you use everyday and are quite familiar with. Always seek the advice of your Physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard medical advice or delay in seeking it because of something you have read on the http://www.meds-hut.com



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