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Menopause equals mood swings. You know, where the slightest request from your husband can cause you to go off. Or perhaps the cries of your child for a new Playstation game makes you lose it. Mood swings, which can trigger the sudden onset of crying, play a significant role in the menopause game and are often one of the first things women notices that causes her to suspect perimenopause. Characteristics of menopausal mood changes include extreme irritability, concentrated anxiety, depression, indifference (neutral feeling to both good and bad situations), and nervousness.