Kalyani Rajalingham

Kalyani Rajalingham

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Kalyani Rajalingham Free Articles

Bioweapons from XNA, a Nuclease Resistant Synthetic Genetic Polymer that can Supplant DNA

Containment and safety issues pertaining to synthetic biology has led to the synthesis of artificial nucleotides that can form synthetic genetic polymers known as Xeno nucleic acids (XNA). Xeno nucleic acids are versatile molecules that can be used to store, transfer, and propagate genetic information; they can also be used as drugs, sensors, catalysts, and regulatory molecules. In this paper, I discuss both the positive and negative applications of xenotechnology; in particular, its potential use as bioweapons are discussed.

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Methadone, buprenorphine, and naltrexone to treat illicit drug addiction

Addiction to illicit drugs is a worldwide problem that affects millions of individuals. Methadone, buprenorphine, and naltrexone are a few of the known anti-addiction drugs with proven efficacy. The goal of this paper is to review said anti-addiction drugs.

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Drugs: From Test Tube to the Shelf

Drugs, prescribed or shelved, all begin in a test tube....

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Tropical application of iodine as an alternative solution for dermal infection of Candida albicans

Abstract Candida albicans is an opportunistic human pathogen responsible for a number of diseases in immunocompromised, and immunocompetent individuals. There are a few drugs available for treatment; however, they face the issue of clinical resistance – Candida albicans can evolve to be resistant to said drugs. Herein, I suggest an alternate therapy – the use of iodine – to clear fungal population as iodine can annihilate Candida albicans in less than 30 seconds.

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Genetic Engineering of Crops

Genetic Engineering can generate plants with many a trait - from plants that can grow in salt water to those that can withstand extreme weather conditions.

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D2 occupancy and weight of patient for controlling extrapyramidal symptoms

First generation antipsychotics are typically accompanied by extrapyramidal side effects while second and third generation antipsychotics are accompanied by metabolic side effects. In particular, the D2 occupancy has been linked to side effects – a D2 occupancy greater than 85% typically results in extrapyramidal side effects.

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