Surgical Treatment for Severe Dry Eyes

May 5
20:11

2024

Peter Raus MD

Peter Raus MD

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Discover the innovative surgical solution for severe dry eye syndrome: transplantation of labial salivary glands to the eyelids. This technique offers a promising alternative when conventional treatments fall short, providing significant relief for patients suffering from this chronic condition.

Understanding Dry Eye Syndrome

Dry eye syndrome,Surgical Treatment for Severe Dry Eyes Articles characterized by insufficient lubrication on the surface of the eye, is a prevalent condition affecting millions globally. It is particularly common among individuals over the age of 50, but younger populations are not immune. Various factors, including autoimmune diseases, certain medications, and environmental conditions, can contribute to dry eyes. Traditional treatments typically involve the use of artificial tears or gels, which provide only temporary relief. In more persistent cases, silicone plugs may be inserted into the tear ducts to prevent drainage, though this can increase the risk of infection by trapping bacteria.

A Breakthrough in Treatment: Labial Salivary Gland Transplantation

In recent years, a groundbreaking approach was pioneered by Professor Juan Murube at Alcalá University in Madrid, Spain. His research revealed that the secretions from the salivary glands in the lower lip closely mimic the composition of natural tears. Building on this discovery, Murube developed a surgical method to transplant these glands to the inner side of the eyelids, offering a more natural and sustainable source of eye lubrication.

The Surgical Procedure

The procedure involves the following steps:

  1. Under general anesthesia, a small section of the labial mucosa and the underlying salivary glands are carefully removed using radiosurgery, which minimizes bleeding and promotes quicker healing.
  2. The harvested glands are then transplanted to the conjunctival side of the eyelid.
  3. The area is stitched using a running suture technique, which is generally removed two weeks post-operation.

Patients typically require only a one-night stay in the hospital and can experience an improvement in symptoms shortly after the removal of sutures, reducing the need for artificial tears.

Clinical Outcomes and Research

Initial results have been promising. Biopsies taken from the transplanted tissue at 18 and 36 months post-operation confirm the viability and continued function of the glands. As of June 2007, 18 eyes had been treated using this technique, with most patients reporting a significant decrease in dry eye symptoms.

Conclusion and Future Directions

While more research is needed to fully validate this technique, the use of labial salivary gland transplantation offers a viable solution for severe cases of dry eye syndrome where other treatments have failed. It is important to note, however, that this surgery is recommended only for severe cases and is not a first-line treatment for milder forms of dry eyes.

For further reading on dry eye syndrome and its treatments, reputable sources such as the Mayo Clinic and National Eye Institute provide comprehensive overviews and updates on the latest research in the field.