Astaxanthin also called ASTA, is a purple crystalline powder, insoluble in water, soluble in a solvent such as dimethyl sulfoxide, acetone, chloroform. The Astaxanthin is extremely unstable when exposed to light, heat easily biodegradable.
In 1938 scientists the first time isolated this natural antioxidant named astaxanthin from lobster. In the ensuing decades, the scientists figure out the structure and biological activity of this antioxidant.
Astaxanthin is a red carotenoid, the highest-level product for the synthesis of carotenoids, ²-carotene, lutein, canthaxanthin, lycopene are carotenoids synthesis intermediates. Therefore, in nature, astaxanthin has the strongest antioxidant activity. According to cosmetic raw material suppliers, it also has the role of anti-aging, anti-tumor, preventing cardiovascular diseases.
Astaxanthin is a chain breaking antioxidants, has strong antioxidant effect. The scientists compared with carotenoids which the structure is similar, but the conjugated double bond number is different, such as lutein, zeaxanthin, lycopene, different zeaxanthin. Carotene and its derivatives in oxidation, the quenching ability of active oxygen increased with the conjugated double bond, wherein astaxanthin with the strongest antioxidant capacity. Use containing ferrous ion of heme protein as a free radical generator, linoleic acid for the receiver, detection of various carotenoids and tocopherols and its derivatives ( VE ) free radical scavenging dose ratio. Researches found that the capacity of astaxanthin scavenging free radical is the strongest, think of carotene and its derivatives in hydroxy and keto existence and the numbers is very important for the free radical scavenging effect.
The biologists’ experimental results show that, cancer is closely related to human genetics and somatic abnormal splitting. In the process of human metabolism, because get the influence of external environment, particulate cell chromosome mutation and mitotic abnormalities, make certain tissue pathologic hyperplasia, so that normal cells turn into cancer cells.
Gene is a subject record various human information, also known as DNA, is double helical chain structure, its mechanism is very stable. In a strong external force, this extremely stable structure will collapse, fracture. When gene chain collapse, fracture, intracellular free nucleic acids will on gene chain repair and reconstruction, in this process, the original gene chain information may have lost, increase or completely rewritten. Then, these cells can be turned into a weird, from which they split to the cell, is the arch-criminal of various diseases, cancer is one of the typical.
Information supported by astaxanthin suppliers, astaxanthin has a strong anti-cancer effect. Effect of astaxanthin on liver cancer show that, astaxanthin in vivo toxicity mechanism induced DNA single strand breaks has reduced effect, reduce aflatoxin B1 and DNA liver and plasma albumin combine, and promoting the in vitro metabolism for another toxic weak aflatoxin M1.
Dietary supplementation of astaxanthin can inhibit breast tumor growth, which greatly reduces the incidence of breast carcinoma, this function is stronger than ² - carotene and canthaxanthin. Enlargement of the prostate gland is mainly caused by 5-a- reductase, astaxanthin can effectively inhibit the enzyme activity, therefore complement astaxanthin is considered to be the effective way to prevent prostate hyperplasia and prostate cancer. Astaxanthin, can regulate gene expression and induces intercellular information transfer process. Cell gap regulate the communication that cell growth information needed, more important is that it can inhibit cancer cell proliferation.
Source:http://www.cosprm.com
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