Isobutyryl Chloride Manufacturer CAS NO 79-30-1

Shree Ganesh Chemicals specialises in the development and supply of fine chemicals to the Pharmaceutical, Agrochemical, Aroma, Polymer and Electronic industries. Isobutyryl Chloride Manufacturer CAS NO 79-30-1 is an example of a Shree Ganesh Chemicals developed product. This product is utilised in a range of applications.

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Acyl is a radical formed from an organic acid by removal of a hydroxyl group. The general formula of acyl compound is RCO-. Acyl halide is one of a large group of organic substances containing the halocarbonyl group, have the general formula RCO·X, where X is a halogen atom (fluorine, chlorine, bromine, iodine, and astatine) and R may be aliphatic, alicyclic, aromatic, and H etc. In substitutive chemical nomenclature, their names are formed by adding ‘-oyl’ as a suffix to the name of the parent compound; ethanoyl chloride, CH3COCl, is an example. The terms acyl and aroyl halides refer to aliphatic or aromatic derivatives, respectively. Acyl halides are made by replacing the -OH group in carboxylic acids by halogen using halogenating agents. They react readily with water, alcohols, and amines and are widely used in organic synthetic process whereby the acyl group is incorporated into the target molecules by substitution of addition-elimination sequence called acylation reaction.  Acylation reaction involves substitution by an electron donor (nucleophile) at the electrophilic carbonyl group (C=O). Common nucleophiles in the acylation reaction are aliphatic and aromatic alcohols, both of which give rise to esters and amines (RNH2) which give amides. The carboxylic acid (X = OH) itself can function as an acylating agent when it is protonated by a strong acid catalyst as in the direct esterification of an alcohol. Two common acylation agents, with the general formula RCOX, are acid halides (X = halogen atom) and anhydrides (X = OCOR). Schotten-Baumann reaction is an acylation reaction that uses an acid chloride in the presence of dilute alkali to acylate the hydroxyl and amino group of organic compounds. There are also other acylating agents. Acyl halide compounds are used as an intermediate for agrochemicals and pharmaceuticals, dyes, and peroxide compounds as well as textile auxiliaries, emulsifiers.

CAS No.79-30-1

Chemical Name:Isobutyryl chloride

SynonymsIBCL;isobutyryl;ISOBUTRYL CHLORIDE;ISOBUTANOYLCHLORIDE;Isoburyryl chloride;ISOBUTYRYL CHLORIDE;ISOBUTYROYL CHLORIDE;chloroisopropylketone;IsobutyrylChloride>Isobutyrylchloride,98%

CBNumber:CB8854405

Molecular Formula:C4H7ClO

Formula Weight:106.55

Isobutyryl chloride Properties

Melting point:-90 °C

Boiling point:91-93 °C(lit.)

Density 1.017 g/mL at 25 °C(lit.)

vapor pressure 0.07 mm Hg ( 20 °C)

refractive index n20/D 1.407(lit.)

Flash point:34 °F

storage temp. Store at RT.

solubility Miscible with chloroform, glacial acetic acid, ether, toluene, methylene chloride and benzene.

form Liquid

color Clear

OdorStench

PH<7 (H2O)

explosive limit2.1-8.2%(V)

Water Solubility Reacts

Sensitive Moisture Sensitive

BRN 605393

CAS DataBase Reference79-30-1(CAS DataBase Reference)

EWG’s Food Scores1

FDA UNII6617F0VJZC

NIST Chemistry Reference2-Methylpropanoyl chloride(79-30-1)

EPA Substance Registry SystemPropanoyl chloride, 2-methyl- (79-30-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 

GHS02,GHS05

Signal word Danger

Hazard statements H225-H314

Precautionary statements P210-P280-P305+P351+P338-P310-P260h-P303+P361+P353-P405-P501a

Hazard Codes F,C,T

Risk Statements 11-35-23

Safety Statements 16-23-26-36-45-36/37/39-28A

RIDADR  UN 2395 3/PG 2

WGK Germany  1

RTECS  UC3944000

F 13

Autoignition Temperature325 °C

Hazard Note Highly Flammable/Corrosive/Moisture Sensitive

TSCA Yes

HazardClass 3

PackingGroup II

HS Code 29147090

HS Code  29159080

Isobutyryl chloride Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid.Soluble in ether; reacts with water and alcohol.

Uses

Usually used in the synthesis of fully isobutyramide terminated hyperbranched polyethylenimines,the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum.

General Description

A colorless liquid. Flash point near 50°F. Irritates skin, eyes and mucous membranes. Toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Produces corrosive toxic fumes containing HCl on contact with moist air. Decomposes in water.

Reactivity Profile

Isobutyryl chloride is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Low toxicity by inhalation. A severe eye irritant.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Isobutyryl chloride Preparation Products And Raw materials

Raw materials

Isobutyric acid Sulfur dioxide Thioacetic acid Methacrylic acid 1-(4,5-dihydrooxazol-2-yl)acetone 2-METHYL-2-OXAZOLINE Isobutyric acid hydrazide 1,3,5-TRIMETHYL-2-(TRICHLOROMETHYL)BENZENE 2,4,6-Trimethylbenzoyl chloride DCM Isobutyraldehyde

Preparation Products

D-(S)-3-acetylthio-2-methylpropionylL-proline Isobutyrophenone Flutamide 1-Chloro-N,N,2-trimethylpropenylamine ISOBUTYRIC ACID ISOPROPYL ESTER 3′-Trifluoromethylisobutyranilide BUCILLAMINE Isobutyramide Etofenprox 2,2-DIMETHYL-3-(2-METHYLPROP-1-ENYL)CYCLOPROPANECARBOXYLIC ACID Propanoic acid, 2-methyl-2-[[(trimethylsilyl)oxy]sulfonyl]-, trimethylsilyl ester

alkyl amines chemicals products