Canada Drug Back-ups a New Nerve Pain Treatment in the Form of Cell Transplant

Aside from generic Neurontin 300mg, which affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain, a new study in mice suggests that scientists may someday be able to treat nerve pain by transplanting embryonic nerve cells to restore a broken nervous system. 

"Nothing that gets rid of the pain works for a long period of time," said study co-author Allan Basbaum, chair of the department of anatomy at the University of California, San Francisco. "The problem is that even if drugs sort of work, they work everywhere in the body and inevitably have adverse side effects like sedation and mental clouding." 

"Nerve pain can strike a variety of types of patients, from those who have had shingles or undergone chemotherapy to those with diabetes. Scientists think certain nerve cells become damaged or lost, and lose the ability to regulate the pain signals that go to the brain," Basbaum said. 

"Some of the cells developed into neurons. Within four weeks, the mice lost their hypersensitivity." Basbaum said, "The findings show unequivocally that the cells integrated into the nervous system of the mice." If this is found feasible in humans, to buy Neurontincheap will no longer be an option. 

"The next step is to inject human embryonic nerve cells into mice that are genetically engineered to not reject human tissue. We want to do the groundwork to learn how to handle human cells," Basbaum said. 

"The ultimate goal is to test the treatment in humans," Basbaum said. "But if the cells don't integrate as they do in the mouse, or the cells don't survive, then it doesn't work." 

He said, "the potential cost of the procedure isn't known. Any work with human embryonic cells could create controversy because they're derived from human embryos. However, scientists are trying to find alternative ways to develop the cells." 

Laura Stone, an assistant professor at McGill University's Alan Edwards Center for Research on Pain in Montreal, praised the study. 

"The research demonstrates that transplantation of cells into the spinal cord could be used as a strategy perhaps not only in chronic pain but in spinal cord injury or other neurodegenerative disorders," she said. 

"Still, the treatment that worked in mice might not work in humans. Even if it does, an available treatment for people would be many, many years away," Stone added. 

"In the big picture, however, there has been an enormous amount of progress in the last 20 years on understanding basic mechanisms underlying chronic pain in general and neuropathic pain in particular," Stone said. "We as a field have identified many new possible drug targets that were unknown just a few years ago." Canada drug available will continue to maintain their established dedication in carrying out missions to progress in the health arena. 

Organ transplantation is the moving of an organ from one body to another or from a donor site on the patient's own body, for the purpose of replacing the recipient's damaged or absent organ. The emerging field of regenerative medicine is allowing scientists and engineers to create organs to be re-grown from the patient's own cells (stem cells, or cells extracted from the failing organs). Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.