Canada Pharmacy Drug Fights Bladder Cancer Risks

People with type 2 diabetes taking Actos (pioglitazone) to control blood sugar may put themselves at risk for bladder cancer, and to buy Zofran Canada may be prescribed by their doctors once the treatment for bladder cancer ends to prevent nausea and vomiting. 

"We believe physicians, patients and regulatory agencies should be aware of this association when assessing the overall risks and benefits of this therapy," said lead researcher Laurent Azoulay, from the Center for Clinical Epidemiology at the Lady Davis Institute at Jewish General Hospital in Montreal. 

"The association between the use of pioglitazone and bladder cancer is controversial, with several studies reporting conflicting results, from modest increased risks to no association," said Azoulay, who also is an assistant professor in the oncology department at McGill University in Montreal. 

Dr. Spyros Mezitis, an endocrinologist at Lenox Hill Hospital in New York City, said "we need to be more careful with the use of this medication." 

The whole class of these drugs has come under fire, he said. "If there are more studies like this, we will not be using this medication," he added. 

Mezitis said he starts new type 2 diabetes patients on other drugs such as metformin to control blood sugar, rather than Actos. Because it's a generic drug, metformin also is less expensive than Actos. 

Mezitis also thinks more patients with type 2 diabetes will get insulin earlier instead of using drugs like Actos. "We have to tailor treatment to each patient, and there are other ways of controlling blood sugar," he said. 

Another expert, Dr. Joel Zonszein, a professor of clinical medicine at Albert Einstein College of Medicine and an endocrinologist at the Clinical Diabetes Center at Montefiore Medical Center in New York City, said he thinks the study is weak, and the risk of bladder cancer is small. 

"There is an important role for these medications," he said. "I am probably one of the last doctors who is still supporting the use of these medications." Generic Zofran cheap will surely aid patients undergoing bladder cancer treatments and medications. 

Zonszein said he starts patients on Actos in combination with other drugs such as metformin to aggressively lower blood sugar. Patients, however, need to know the risks, he said. 

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