Canada Pharmacy Links Blood Clot to Non-Pill Contraceptives

Few females using contraceptives other than birth control pills may have a boosted threat for critical blood clots.  Hence, they need to buy Warfarin. 

"These alternate hormone-releasing birth control methods include skin patches, implants and vaginal rings. To reduce the risk, women who use these should consider switching to the pill," the researchers said. 

"The transdermal patch and vaginal ring confer at least a sixfold increased risk of venous thrombosis as combined pills with desogestrel or drospirenone, a risk which is about twice the risk among women using second-generation pills with levonorgestrel," said lead researcher Dr. Ojvind Lidegaard, a professor of obstetrics and gynecology at the University of Copenhagen. 

However, hormone-releasing intrauterine devices (IUDs) do not increase the risk of venous thrombosis, he said.

"Women should be informed about these risks in order to be able to choose the most appropriate hormonal contraceptive product," Lidegaard said. "There are hormonal contraceptive alternatives which confer less or no risk of venous thrombosis." 

"For women who used an implant that contained only progestogen, the increased risk for clots was very small. There was no risk for women using a progesterone-only IUD and it may have has a protective effect," the researchers noted. Generic warfarin is a great help. 

"For the majority of young women, the recommendation is second-generation combined pill with levonorgestrel, and for women who have given birth, that a hormone-releasing intrauterine device is an attractive option, because it at the same time does not increase the risk of venous thrombosis, perhaps even protects against them, and reduces menstrual complaints," Lidegaard said. 

Dr. Elizabeth Poynor, a gynecologist and pelvic surgeon at Lenox Hill Hospital in New York City, commented that "over the past years, newer versions of combined hormonal contraception have been developed." 

"While these types of transdermal hormonal contraceptives may be more convenient for some women and lead to better compliance with appropriate use, they have their own set of medical side effects and concerns," she said. 

"This highlights the importance of reviewing the risks, benefits and alternatives among differing types of medications within the same broad category," Poynor added. 

"For some women, these types of medications are extremely useful, but their potentially elevated risk of thrombosis should be reviewed before prescribing them," Poynor stressed. Canada pharmacy has to be cautious in checking the prescriptions given to them by the patients. 

blood clot, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors). A thrombus is normal in cases of injury, but pathologic in instances of thrombosis. 

Mural thrombi are thrombi adherent to the vessel wall. They are not occlusive and affect large vessels, such as heart and aorta. Grossly they appear grey-red with alternating light and dark lines (lines of Zahn) which represent bands of fibrin (lighter) with entrapped white blood cells and red blood cells (darker). 

Specifically, a thrombus is the inappropriate activation of the hemostatic process in an uninjured or slightly injured vessel. A thrombus in a large blood vessel will decrease blood flow through that vessel (termed a mural thrombus). In a small blood vessel, blood flow may be completely cut-off (termed an occlusive thrombus) resulting in death of tissue supplied by that vessel. If a thrombus dislodges and becomes free-floating, it is termed as an embolus.