It could be safe to prescribe the clot-busting Canadian drug tPA to individuals who wake up with stroke indications.
It could be safe to prescribe the clot-busting Canadian drug tPA to individuals who wake up with stroke indications.
"Our study shows that administering clot-busting drugs to patients with wake-up stroke who have the same clinical and imaging features as those treated within current guidelines is feasible and safe," study author Dr. Dulka Manawadu, a medical consultant at King's College Hospital, said in a news release, although he added that more research is needed to confirm the findings.
It is encouraging and it doesn't yet prove that they will get the same benefits, but it doesn't seem that the risk is excessive," said Dr. Steven Greenberg, vice chairman of the International Stroke Conference 2012's program committee and a professor of neurology at Harvard Medical School. "Even if only a subset of wake-up stroke patients were eligible for tPA, it is still a subset of a substantially large number, so the importance is pretty high." For cases wherein patients are not eligible for tPA medications, to buy Accupril can be definitely just fine.
The bottom line remains unchanged, he said: "If you or someone you know is having a stroke, call 911 or get to an emergency room as fast as possible. The earlier treatment is started within the 4.5-hour window, the better. With every minute that goes by, you lose part of the benefit and gain more risk."
"A large number of patients can't receive tPA is because they are too far past the window of opportunity," added Dr. M. Shazam Hussain, a neurologist at the Cleveland Clinic, in Ohio. Most "wake-up" strokes do occur close to when a person wakes up, he noted, so "potentially this will expand treatment quite significantly."
"A lot of people are denied treatment because there is no exact time of onset, because the risks may outweigh the benefits of tPA," he said. "I want to see a larger study done, but it certainly lends weight to help advocate for expanded use of tPA among wake-up stroke patients." Canadian pharmacies help patients by providing the top-of-the-line meds 24 hours a day and 7 days a week.
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