Complete Information on Churg-Strauss syndrome

Churg and Strauss discovered that the presence of granulomas as well as the abundance of eosinophils distinguished this disease from PAN. Another name for Churg-Strauss syndrome is allergic granulomatosis. The disease may involve any organ, most commonly it affects your lungs and skin. The restricted blood flow to these organs can cause temporary or permanent damage. Churg-Strauss syndrome is rare. The cause of this syndrome is not known.

But it involves an abnormal over-activation of the immune system in a person with underlying bronchospastic lung disease (asthma). While Churg-Strauss syndrome has been reported to be associated with certain asthma medications, called leukotriene modifiers. The disease can occur at any age, but it's more commonly diagnosed in middle-aged people. People older than 65 are unlikely to develop Churg-Strauss syndrome. Other common names for CSS are allergic granulomatosis and allergic angiitis. Churg-Strauss syndrome causes fever, weight loss, and sinus or nasal passage inflammation in the patient with asthma. Fatigue is common.

Cough, shortness of breather, and chest pain can happen as the lungs are affected by vasculitis. Skin lumps, called nodules, can seem on the extremities. Diarrhea and pain in the belly happen with blood vessel inflammation within the stomach. The bladder and prostate gland can get inflamed. Churg-Strauss syndrome like complication is reported in folk whose withdrawal of oral steroids is too facilitated by inhaled steroids. This complication is likely related to steroid withdrawal, which unmasks underlying Churg-Strauss syndrome, quite than to the drugs themselves.

Medications that repress the exempt structure kind the basis of handling for CSS. Prednisone is the medicine normally used. Most patients with CSS react favorably to corticosteroid therapy. Additional handling options include inhaled steroids, cyclophosphamide (cytoxan), azathioprine (imuran) , and high-dose intravenous exempt globulin (IVIG) have been used in patients with serious disease or disease that is insensitive to corticosteroids. Use of calcium supplements, vitamin D, hormone successor therapy and/or bisphosphonates can assist defend against ivory mineral departure.