Cogan's syndrome is an uncommon, rheumatic disease characterized by inflammation of the ears and eyes. Cogan’s syndrome causes symptoms that are related to those of syphilic keratitis although there is no evidence of pox transmission in Cogan’s syndrome.
Cogan’s syndrome primarily targets children and inexperienced adults in their 20’s and 30’s. Cogan’s syndrome often occurs after an influenza-like transmission. Cogan’s syndrome causes heart inflammation, including conditions such as keratitis, iritis, scleritis, or conjunctivitis, associated with equilibrium problems, vertigo and ear ringing (tinnitus
These vestibuloauditory symptoms can advance to speedy multilateral deafness payable to inflammation affecting the 8th cranial heart. Other symptoms include vasculitis, nausea, vertigo, impoverished equilibrium, fever, tiredness, weight departure, vomiting, soft sensibility, and a multilateral blurring of imagination. More seldom, Cogan's syndrome can induce expanded lymph nodes, bold, chest pain, weapon pain and shortness of breather. Systemic cardiac manifestations of Cogan’s syndrome include aortitis, aortic valve deficiency, pleuritis, pericardial effusion, coronary arteritis, and perhaps myocardial infarction.
Hearing loss is often progressive and can lead to permanent deafness within two years without early diagnosis and treatment intervention. Mild eye disease may be treated with anti-inflammatory medications. Anti-inflammatory eye drops are used in cases of mild eye symptoms. If signs of infection occur, antibiotic eye drops can be used. In severe eye disease, oral corticosteroids or immunosuppressive medications such as cyclosporine or cyclophosphamide may be used. In cases where the eye’s blood vessels are damaged, surgical intervention and corneal transplant may be required.
Antihistamines such as diphenhydramine are also used for problems with imbalance. Cochlear implants are used in cases of hearing loss. If excess fluid in the inner ear is causing balance problems, your doctor may prescribe diuretic medications, which increase urination and removal of fluid from the body. When hearing is impaired and does not improve with medical treatment, cochlear implants may be helpful. Cochlear implants are electronic devices that translate sounds into electrical signals that are transmitted to the brain, bypassing the malfunctioning part of the ear. Part of the device is implanted in the ear, and part is worn outside the ear.
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