Eosinophils are associated the reactions allergic-type. The people under this condition have an accumulation of the eosinophils, a type of white cell of blood, in the affected fasce and muscles.
Eosinophilic fasciitis is characterized by tenderness and swelling of the ends caused by the ignition of the fasce and the muscles. The arms, the legs, the trunk, and the face can be affected by diminish, weakness of muscle, and the common changes of the overlying skin. The eosinophilic fasciitis also occurs in the males and the females. The eosinophilic disorder of fasciitis occurs mainly at the old men 40 to 50, but it can occur among women and of the children.
The symptoms of the eosinophilic fasciitis include the fast profit of weight, swelling, the ignition of the followed skin of the induration (to cause orange-peel the aspect) above the former surface of the ends, and the pain of muscle. The eosinophilic fasciitis often occurs after intense exercise at the usually sedentary people and it occurs sometimes after infection with the burgdorferi of Borrelia. One suspect also of toxins to start the eosinophilic fasciitis. One reported that other syndromes hypereosinophilic occur after the ingestion of L-tryptophan and other drugs, in particular drugs of anti-hypertensive.
The treatment with drugs of corticosteroid provides the relief of the symptoms. Drugs anti-inflammatory drugs of Nonsteroidal can also help of the symptoms of relief. The therapy of Adjunctive can be also required some cases. The drugs of Adjunctive include the hydroxychloroquine, the colchicine, the cimétidine, the cyclosporin, the azathioprine, and the methotrexate. The methotrexate of drug of immunize-suppression can provide an additional advantage in the eosinophilic fasciitis of treatment. This methotrexate can reduce the immunized ignition and the need for continuous cortisone drugs. The surgical decompression of the syndrome of tunnel carpal can be required.
