Fibrous dysplasia Detailed Information

Fibrous dysplasia is the most famalier bone abnormality that occurs during the years of growth and development. There are many different types of fibrous dysplasia but, main types is Monostotic fibrous dysplasia , Polyostotic fibrous dysplasia and McCune-Albright syndrome. Monostotic fibrous dysplasia only one bone is affected. Monostotic fibrous dysplasia is most commonly affected site in monostotic fibrous dysplasia is the skull. McCune-Albright syndrome fibrous dysplasia can be associated with hormone disturbances and skin pigment changes.

The cause of fibrous dysplasia is unknown. But a genetic mutation of the Gs alpha gene has been identified in patients with McCune-Albright syndrome. The polyostotic and McCune-Albright forms affect more females than males. This condition occurs in childhood, usually between 3 and 15 years of age. In some cases, fibrous dysplasia has no symptoms Children experience fibrous dysplasia in a wide range of severity. Some experience several symptoms related with endocrine abnormalities, while others show entirely healthy, with little or no evidence of bone or endocrine involvement.

Some common symptoms associated with this condition bone pain, difficulty walking, difficulty walking ,and deformities of the leg or arm and limb length discrepancy. There is no cure for fibrous dysplasia. Bone fractures or deformities are treated as appropriate. Medications called bisphosphonates, including pamidronate (Aredia) and alendronate (Fosamax), are used to inhibit bone breakdown, preserve bone mass and even increase bone density in your spine and hip, reducing the risk of fractures. Oral bisphosphonates are generally well tolerated.

Surgery is recommended in the case of painful or fractured bones or when joints can no longer move freely. Surgery may successfully deal this condition if only one bone is affected. If many bones are affected, it may not be possible to kill every section of diseased tissue. Exercise is very important in maintaining skeletal health and is recommended for patients with fibrous dysplasia. Regular weight bearing exercise helps to strengthen bone, increase joint mobility and maintain a healthy weight. It is important that the exercise program is performed under the supervision of a doctor because a person with fibrous dysplasia is at increased risk of bone fractures.