Haemophilus influenzae

Sep 14
14:12

2008

Juliet Cohen

Juliet Cohen

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Droplets in the air from a sneeze can be inhaled and may also cause infection. There are six generally types of H. influenzae

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Haemophilus influenzae can cause serious invasive disease especially in young children. Invasive disease is usually caused by encapsulated strains of the organism. H. influenzae most commonly causes ear,Haemophilus influenzae Articles eye, or sinus infections, and pneumonia. The H. influenzae bacteria live in the upper respiratory tract and are usually transmitted by close contact with an infected individual. Naturally-acquired disease caused by H. influenzae seems to occur in humans only.

In infants and young children, H. influenzae type b (Hib) causes bacteremia, pneumonia, and acute bacterial meningitis. Occasionally, it causes cellulitis, osteomyelitis, epiglottitis, and joint infections. Hib disease has no sexual predilection; however, women are at risk for postpartum sepsis, tuboovarian abscess, and chronic salpingitis caused by NTHi that colonize the genital tract. Hib disease has decreased to 1.3/100,000 in children. However, Hib remains a major cause of lower respiratory tract infections in infants and children in developing countries where vaccine is not widely used.

Unencapsulated H. influenzae (non-B type) causes ear (otitis media) and eye (conjunctivitis) infections and sinusitis in children, and is associated with pneumonia. Treatment for H. influenzae greatly depends on which area of the body is infected. Antibiotics and supportive care also helpful this condition. Administer parenteral antibiotics (e.g., ceftriaxone, ceftazidime, cefotaxime, ampicillin-sulbactam, fluoroquinolones, and azithromycin) to patients with uncomplicated meningitis for 7-14 days.

Dexamethasone is an important adjunctive treatment in patients with meningitis who are older than 2 months. The use of the Hib conjugate vaccines has reduced the number of cases. Hib vaccines are made from capsular polysaccharide that has been extracted from cultures of Hib bacteria. There are several types of Hib conjugate vaccines available for use. All of the vaccines are approved for use in children 15 months of age and older and some are approved for use in children beginning at 2 months of age. All of the vaccines are considered effective. The vaccines are given by injections.