Natural resveratrol has cis and trans two kinds of structures. These two kinds of structures can combine with glucose to form cis or trans resveratrol glycosides. They are related with the biological activity of resveratrol.
Resveratrol is widespread in seed plants and it is a phytoalexin. There are at least 12 families and 31 genera, 72 species which can found it. The main plants with rich resveratrol are grapes, peanuts and Chinese medicine polygonum cuspidatum , in particular the highest content of the fresh grape skins is 50 ~ 100 ¼g with a dominant position anti-g-style. The studies have shown that resveratrol has a variety of pharmacological effects of anti-tumor, anti cardiovascular disease, anti inflammatory, anti oxidation, liver and nervous system protection. It has become the natural active ingredient that scientists attach great importance to. It has great medicinal value and market outlook.
In the origin of cancer, promotion and developing stage, the inhibition makes resveratrol become a hot research topic in cancer chemoprevention and chemotherapy. That resveratrol is mainly through inhibition of cytochrome enzymes, induction of detoxification enzymes, inhibition of cyclooxygenase, inhibition of protein kinase, and antagonized the role of estrogen and anti-tumor. Hormone receptor, promoting tumor cell differentiation and apoptosis pathway to inhibit tumor cell proliferation. The study showed that resveratrol can inhibit the growth of human oral squamous cell carcinoma, human leukemia, human colon carcinoma, human breast carcinoma, prostate cancer and other cancer cells.
Resveratrol significantly induced apoptosis of human gallbladder cancer cells, cell cycle distribution changes, mainly for the percentage of G2 / M phase cells decreased S phase cells increased. Resveratrol and chia seed anti-leukocyte induced leukocyte differentiation apoptosis and cell cycle remain in the S phase. A growing number of scholars believe that resveratrol is the main function of factors plays cardiovascular protective effects of red wine. The study confirmed that resveratrol trans resveratrol, that the cardiovascular protective effects of polyphenols than red wine have a stronger. Thrombosis is the main reason of myocardial infarction and stroke.
Resveratrol has good anti-inflammatory effects on acute and chronic inflammation. The anti-inflammatory mechanism may be related to inhibition of leukocyte migration, reduce leakage, scavenging oxygen free radicals, inhibit lipid peroxidation, and interfere with the metabolism of arachidonic acid to reduce the generation of inflammatory factors. Resveratrol on the lipoxygenase metabolism of arachidonic acid cyclooxygenase two metabolic pathways are inhibited. It can be reduced metabolites of leukotriene and prostaglandin generation on COX - 2 selective inhibitions.
Polyhydroxy stilbene material mostly has antioxidant and anti free radical roles. Studies have shown that resveratrol has antioxidant, anti-free radical and the pharmacological effects of the arachidonic acid metabolism. It also has an important mechanism of docetaxel multiple biological effects, such as anti tumor, cardiovascular protection, tissue organ damage, liver, shock prevention and care anti etc. The health of biological and pharmacological activity make resveratrol widely used in medicine, health products, cosmetics and food additives. Its roles in the treatment and prevention of cancer, cardiovascular and cerebrovascular disease, dementia, viral hepatitis, inflammatory diseases get more and more awareness. It has abroad clinical application prospect. It is expected to become a new drug for prevention and treatment of many diseasess.Source:http://www.cospcn.com
The application of tungsten in various industries
Steel Industry Most of tungsten applied in the production of special steels. The widely used high-speed steel was containing 9-24% of tungsten, 3.8-4.6% of chromium, 1-5% of vanadium, 4-7% of cobalt, 0.7-1.5% of carbon.
Magic effects of coconut oil
According to records, coconut oil can be regarded as the nobility of skin care plant extracts. It was rich in exotic tension of tropical plants, which can enhance the contractile force of the pores, perfectly beautify and nourish the skin.
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Abamectin and its derivative, emamectin benzoate, have emerged as pivotal substances in the realm of pest control, offering a broad-spectrum efficacy against various pests while maintaining a favorable environmental profile. As the agricultural industry continues to evolve, these compounds have adapted to meet the growing challenges of pest resistance, expanding their market applications and maintaining cost-effectiveness despite rising production costs.
