Resveratrol can control blood glucose

Meanwhile, resveratrol also received evidence (based on the laboratory and the institute of zoology) that it can build up their strength and endurance. For most of major degenerative diseases, including aging, especially cardiovascular disease, neurodegenerative disease, cancer, arthritis and diabetes mellitus, it has a strong protective effect.

The researchers recently studied the effect of resveratrol on insulin sensitivity. It includes vitro outside (cultured cells) and in vivo (in vivo). At first, they didn’t use resveratrol itself but something called SIRT1 endogenous (from the body) protein. It is well known that the protein can be stared by resveratrol. That means resveratrol through the interaction of the chemical can enhance the activity of SIRT1.

The study tried to determine resveratrol can improve insulin sensitivity in vitro. Use a variety of cultured cells, including rat adipocytes and human hepatoma cells and found that resveratrol could significantly improve insulin function (insulin sensitivity within the cell to improve the signal), either in normal or insulin resistance circumstances. In addition to the protein activator, resveratrol can increase (stimulation) of SIRT1 gene, triggered to produce more protein. The data indicate that resveratrol play a role in a SIRT1-dependent manner, that is, its effect may be related to the effect of SIRT1, which consistent with the field the majority of previous studies.

The study examined the ability of resveratrol to improve insulin sensitivity in vivo using mice fed high-fat diet, they can be induced to produce insulin resistance (which the link between obesity and insulin resistance, and this contact is often caused by diabetes). In order to try to compensatory insulin resistance, the pancreas of mice produce large amounts of insulin, resulting in high plasma insulin levels, mice (and humans) is harmful. For these afflicted mice, pharmaceutical raw materials resveratrol can significantly improve insulin sensitivity. The result is that they reduce the amount of insulin required in order to control blood sugar levels and insulin levels were also significantly lower. This is a win-win situation.

Although resveratrol can start the antioxidant system, it is not a major anti-oxidant. And perhaps it should not be called as an antioxidant. Although resveratrol as well as many other polyphenols antioxidants including a large class of compounds called flavonoids in cultured cells (most of the work carried out on cultured cells) showed antioxidant activity, however, they did not play the same role in vivo. It is truly unforgivable in vivo. However, the merit is that they can be proved to have benefits on health. But it is obviously though a completely different mechanism, perhaps the antioxidant system stimulating the body. Source:http://www.cospcn.com