The expelling parasite effect of avermectin

Avermectin has the advantage of getting rid of the pigs’ internal and external parasites at the same time, it has expelling and killing effect on the gastrointestinal nematode parasites, such as ascaris suum, pig gastric round nematodes, hog esophagus nematode (nodular worm) and pig hair nematodes’ adults worm (whipworm) and most of the fourth larval as well as pig worms (lung filaria), pigs crown tail nematode’s adults worms (pig kidneys worm), to the scabies mites and blood lice in pig body surface also have a good killing effect, but to their eggs, it’s no killing effect. Abamectin to the tapeworms and flukes, Balantidium coli, pigs coccidia and the like were no effects.

In these different dosage forms, the 0.2% or 1% of oral premixes made of pure powder is more commonly used, thus put it into the feed with oral administration is more convenient. However, the bioavailability of injections is highest, and after injected to the subcutis, the drug binding with subcutaneous fat can play a certain release effect, so that it not only play a role on killing the infected parasite, but also because the blood drug concentration maintain for a long time, so that can protect the pigs within a certain time would not reinfect because of environmental pollution, parasites, play the dual effect of treating and preventing. Furthermore, compared with oral dosing, the injection dosing is more precise, so when they are conditions should use injections as preferred.

Ivermectin is improved on the basis of abamectin, its advantage is reducing the toxicity, so it should try to use ivermectin, but the price of ivermectin in the market is slightly higher than avermectin. The ivermectin injection were more use 1% formulations to the pigs, generally can be according to the body weight, about 0.3ml per 10kg,  should use short needle injecting under the skin, do not injected into the muscle or blood vessels. The injections program is generally use in about 40-day-old pigs, before the back-up pig breeding, the pregnancy pigs two weeks before delivery should inject one time every week, but in heavier-infected farms should increase one time injection while be transferred to fattening homes, and breeding sows in breeding period should also increase one time injection, to breeding boars, should inject 3 to 4 times every year. Breeding pigs especially those suffering from intractable scabies boars, such as local crust have thick knot, long lasting, can increase the injected dose and the number of using drugs. Per course of treatment can use 1% ivermectin, 0.4ml per 10kg of body weight, injected every 5 to 7 days, continuous using until healed.

The oral powder are almost use 0.2% premixes, while one-time de-worming the small pig group, generally according to per 30kg body weight use 5grams of dosage to mix feeding. If in terms of the whole deworming program and in order to improve the expelling parasite effect, it should better use the gradation hurl method, should be based on the pig's days of age mix 0.2% premixes in per ton of feed, to nursery pigs, growing-finishing pigs, breeding pigs were respectively use 1.5kg, 2.0kg and 2.5kg dosage; to serious infected pigs can increase the dosage to 3.5 kg, if each dose above were converted into pure powder, then it approximately 0.1mg per kilogram of body weight, or every per kilogram of feed contains 2 mg, the pig herd use every kind of dose should be continuous fed with 7 days. The medication time should 1 time respectively in three weeks before the sow delivery and mating, the reserve sows were 1 time before breeding, mating boars 3 times to 4 times a year, the sub pigs transferred to incubation homes should also dosing 1 time. While developing and carrying out the de-worming program should particular pay attention that first time deworming should unify to medicate on all the pigs (except sucking child pig), to eliminate the source of infection.

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