Why does IVF fail with Good Embryos? - Know the Real Reason Behind It

Apr 20
10:52

2022

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There is a lot of information about in-vitro fertilization (IVF) available to the common people now which has made it more accessible but there still remains some lesser-known aspects of the treatment.

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There is a lot of information about in-vitro fertilization (IVF) available to the common people now which has made it more accessible but there still remains some lesser-known aspects of the treatment. People tend to think that IVF is a panacea for all infertility issues and that there’s a near guarantee of success if one adopts this treatment method. However,Why does IVF fail with Good Embryos? - Know the Real Reason Behind It Articles this is untrue. Even the best IVF center in Gurgaon cannot promise you success in IVF, despite being better than most of the country’s other fertility centers. On average, only about 30-40% of the couples getting this treatment are able to have a baby. Why is it so? It’s because there are a lot of factors at play in making an IVF cycle successful and some of them are even out of human control. 

So, if you are planning on getting the treatment or have taken it and failed, here are some potential causes of failure that you should know about.  

Some common reasons for IVF failure

  • Lower egg count is a common cause; sometimes, even the ovulation medicines fail to work.
  • Poor egg quality is another possible cause
  • Lower sperm count also lowers the chances of fertilization
  • Poor sperm quality (low motility, misshapen sperms, or damaged sperms) can cause issues (you can take a semen test in Gurgaon to check for most of these issues)
  • Poor quality of embryo or faulty embryo selection can lead to early miscarriage
  • Suboptimal lab conditions can lead to weakening or even death of embryos prior to implantation
  • Imprecise and inefficient egg retrieval and/or embryo implantation are 2 critical errors in IVF that can cause the cycle to fail; implanting the embryo outside the uterus can lead to an ectopic pregnancy which soon ends in a miscarriage
  • The woman’s age is a crucial factor, those less than 35 years old have about 50% chances of succeeding whereas those above 42 have only 4% chances of conceiving
  • Leading an unhealthy lifestyle can also lead to IVF failure
  • About 10% of the IVF failures are attributed to unknown causes

To avoid most of these problems, you should choose an experienced doctor and the best IUI center in Gurgaon. However, there is yet another issue some people face, their doctor told them that the embryo was healthy but they still didn’t succeed in conceiving. Let’s see why this may happen.

Can IVF fail even with a good embryo?

Although a ‘good’ embryo is essential for the continuation of a pregnancy, it doesn’t always guarantee IVF success. This is a disappointing fact to digest but it might happen due to 3 reasons. One, as noted above, poor implantation of even a healthy embryo will lead to IVF failure. Two, the seemingly ‘good’ embryo was declared so by the embryologist based on morphological markers which may be deceiving as the outer form may not reveal the qualitative problems. Sometimes, the embryo has chromosomal abnormalities which cannot be detected based on its outer look and need special screening tests to be diagnosed.

The third reason is an unreceptive uterus. The receptivity may be due to a condition like endometriosis, fibroids, etc., or it may be a result of overactive immune cells which cause the uterus to attack the embryo. Both these conditions cause an early abortion or even implantation failure (which, if it happens more than once, is called ‘recurrent implantation failure’). 

How to ensure IVF success after having failed before?

Most couples will experience difficulties in their 1st IVF cycle, some might even need 3 to 5 cycles to get pregnant. But no matter what the reasons for the earlier failed IVF cycles were, you can still have hope for the future. You have to talk to your doctor about what went wrong. They may suggest various tests like laparoscopy, preimplantation genetic screening (PGS), endometrial receptivity assay (ERA), a sperm DNA fragmentation test, etc., to confirm the reason for failure. Then, you’ll have to work with your doctor to avoid that (or those) errors or treat the underlying conditions before you proceed to the next IVF cycle. Also, it is better to take a break between two cycles, it will give your body and you the essential time to recover from the previous failed attempts and get ready for the next one. Lastly, don’t take too much pressure as anxiety can reduce your chances of conceiving. Just relax and try again, if it’s any help, people have been known to conceive naturally after a few failed IVF cycles.