The inoxidizability and integrate detoxification of glutathione

Sep 21
15:41

2012

David Yvon

David Yvon

  • Share this article on Facebook
  • Share this article on Twitter
  • Share this article on Linkedin

Reduced glutathione plays an important role in the process of our efforts to safeguard the health, helps white blood cells to kill bacteria and prevent vitamin C and E being oxy-genated, prevent the formation of stroke and cataract, and can help skin whitening.

mediaimage

However,The inoxidizability and integrate detoxification of glutathione    Articles due to the accelerated pace of modern life, liver is hard to meet the demand of human, and can not guarantee always secrete enough of reduced glutathione, so we are required reduced glutathione to give adequate attention and timely supply.

Glutathione widespread in animals, plants, the baker's yeast, wheat germ and animal liver are with the pretty high level. Also the glutathione with reduced and oxidized, the reduced glutathione occupied majority under physiological conditions. It can strengthen the immune activity of the body's immune system, for radiation, radioactive drugs or leukopenia caused by anticancer drugs and other symptoms can have a protective effect, from oxidative damage, prevent red blood cell hemolysis and promote the reduction of methemoglobin, anoxemia, nausea and discomfort caused by liver disease mitigation. More as a functional food base material, widely used in anti-aging, enhance immunity, anti-tumor and other functional food.

Reduced glutathione is a peptide in the cytoplasm of human natural synthesis, consists of  glutamic acid, cysteine and glycine, containing a mercapto group, is widely distributed in various organs of the body, show the important role for the maintenance of cell biological functions. Reduced glutathione antioxidant integrate the role of detoxification, antioxidants counteract free radical damage to the human body. Free radicals are the contributing factors that lead to aging and disease. We contact free radicals with every day from diet, environment, household chemicals, and other aspects of sources. Reduced glutathione glyceraldehyde phosphate dehydrogenase cofactor glyoxal enzymes triose dehydrogenase coenzyme involved in the body of the citric acid cycle and glucose metabolism. Can activate a variety of enzymes, thereby contributing to the sugar, fat and protein metabolism, and can affect the metabolic processes of the cells; Through the combination of thiol and free radicals, can be converted into easy metabolic acid material so as to accelerate the excretion of free radicals, which helps to reduce the side effects of chemotherapy and radiotherapy.

Reduced glutathione has two important effects: antioxidant and detoxification integration. Because it easy to combined with iodoacetic acid, lead, mercury, arsenic and other heavy metals, and has a very important physiological role is the integration of detoxification, involved in the biotransformation of some drugs, which transformed into the body of harmful poisons harmless substances excreted.

Glutathione applicable to a variety of liver diseases, for liver disease caused by alcoholism, drug-induced liver disease have a more noticeable effect, the role of chronic active hepatitis B, hepatitis C, improve symptoms and liver function. In addition, due to the amino acid is a key ingredient for skin whitening agents, reduced glutathione also can be used as cosmetic raw material, which contains vitamin C can also make the skin smooth, flawless and wrinkles.

Chemotherapy in patients with drug injection, should be advance 15 minutes to put 1.5g/m2 of this product dissolved in 100 ml of normal saline, intravenous infusion within 15 minutes, 2-5 days of daily intramuscular injection of this product 600mg. For the prevention of urinary system damage, it is recommended that immediately after intravenous injection of the goods in the cyclophosphamide injection infusion is completed within 15 minutes; Shun chloride platinum chemotherapy, the recommended amount of this product should not exceed 35mg/mg cis chloride platinum , so as not to affect the effect of chemotherapy. Alcoholic liver injury: intravenous saline the 250ml plus FDA 1200mg once a day.

The glutathione manufacturer reminded that, reduced glutathione should be used under medical supervision, must be completely dissolved before injection, the appearance is clear, colorless; dissolved this product can be stored at room temperature for 2 hours, 0 ~ 5  save 8 hours. Do not mixed use with vitamin B12, the menadione, Calcium Pantothenate, orotic acid, antihistamines preparations, sulfa drugs and tetracycline.

Source:http://www.cosprm.com