Bilateral Renal Agenesis is a hereditary disorder characterized by a bankruptcy of the kidneys to produce in a fetus. This absence of kidneys causes an inadequacy of amniotic fluid in a pregnant woman.
This disorder is more popular in infants born of a parent who has a kidney deformity, especially the absence of one kidney. Kidneys execute many significant bodily functions. Kidneys filter waste and additional fluid from the blood, hold a robust blood degree of electrolytes and minerals, such as sodium, phosphorus, calcium, and potassium, assistance to preserve robust blood force, and departure hormones that are significant for bodily functions.
Normally, there are two fist-sized kidneys submit, one on each position of the spinal editorial at the backwards just below the ribcage. Each kidney contains infinitesimal filter lobules called nephrons that transportation bodily waste products from the bloodstream to the urinary structure. Functional nephrons are crucial for maintaining bodily functions and for eliminating the buildup of waste products that can be severe. Neonates born with multilateral renal agenesis are instantly placed in the neonatal intense maintenance unit. The degree of renal and respiratory role is instantly assessed. Evaluation is too made of any new malformations in bodily systems.
Once the long-term prognosis of survival is determined, a treatment plan can be addressed. If lung development is sufficient to retort to treatment, mechanical ventilation can supply respiratory support. Management of renal failure involves a complex course of action taken to address all the consequent complications. Adequate nutrition with restricted sodium and fluid intake may be achieved through a nasogastric feeding tube. Medications and vitamin supplementation can be used to address electrolyte imbalances from lack of kidney function. Because the kidney is responsible for vitamin D formation, vitamin D therapy is important.
Calcium carbonate is also supplemented because the kidneys are not present to manage calcium levels in the blood. To treat the hypertension associated with bilateral renal agenesis, diuretic agents (Lasix) are used. Diuretic agents further the excretion of water and electrolytes from the body. They decrease blood pressure by decreasing the amount of fluid present in the blood vessels. Other hypertensive medications may also be used, as is appropriate for the patient's age. Dialysis is required to function as a blood filter replacement for the kidney. Frequent dialysis treatments remain necessary until the infant is old enough to receive a kidney transplant.
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