Stevens Johnsons Syndrome Diagnosis and Treatment

Dec 24
11:01

2007

Juliet Cohen

Juliet Cohen

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SJS is a rare condition, with a reported incidence of around one case per million people per year.

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Stevens Johnsons Syndrome is a dangerous problem of the skin. It is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.SJS is an immune-complex–mediated hypersensitivity disorder that may be caused by many drugs,Stevens Johnsons Syndrome Diagnosis and Treatment Articles viral infections, and malignancies. The skin rash of SJS consists of erythematous (red) papules, vesicles, bullae. There may also be iris lesions. The mucosal lesions include conjunctivitis as well as oral and genital ulcers. The most frequent complications of SJS are keratitis, uveitis, and perforation of the globe of the eye all of which may result in permanent visual impairment.

SJS occurs with a worldwide distribution similar in etiology and occurrence to that in the United States. These skin diseases can cause massive pain, suffering and anxiety. People that have taken or are taking medications such as the ones mentioned above are urged to familiarise themselves with the symptoms of SJS (Stevens-Johnson Syndrome) and Toxic Epidermal Necrolysis. Viral infections, diseases that decrease your immunity, human immunodeficiency virus (HIV), and systemic lupus erythematosus a chronic inflammatory disease increase your risk of developing Stevens-Johnson syndrome. Avoid medications that cause this skin disease. Complete care is very effective and in starting treatment of Stevens Johnsons Syndrome is just like burns.

Cyclosporine and cyclophosphamide can be used to reduce Stevens Johnsons Syndrome. Treatment with corticosteroids is controversial since it might aggravate the condition or increase risk of secondary infections. Other agents have been used, including cyclophosphamide and cyclosporine, but none have exhibited much therapeutic success. Use of antiseptics and anesthetics may help in treatment of SJS. In severe cases, immunoglobulin intravenous (IGIV) to halt the process of Stevens-Johnson syndrome. Osteo-odonto-keratoprosthesis is a revolutionary treatment which involves the usage of the patients own mucosal cells from the buccal cavity as a culture over the eye and placing a cylinder crafted from the patients canine tooth{ also called as the eye toth } in the place of the pupil.