The discovery of biotin

Oct 31 10:36 2012 David Yvon Print This Article

Biotin, also known as vitamin H, coenzyme R, is a water-soluble vitamin, also belonging to the vitamin b family, ranked 7th in the B family, is also known as vitamin B7. 

Synthetic vitamin C needs the help of this substance. An integral part of the body's fat metabolism and protein metabolism,Guest Posting so it is an indispensable nutrient to maintain growth and health. It is present in foods such as liver, egg yolks, milk, yeast.

Biotin was first discovered in 1935. In fact, as early as in the early 20th century, scientists had been discovered that humans and animals eat raw eggs is harmful, long-term consumption can cause loss of appetite, general weakness, muscle pain, skin inflammation. After cooking its toxicity disappears, what’s the matter about it? In 1936, biotin manufacturer isolated a crystalline substance from the cooked egg yolk, this substance is a substance necessary for yeast growth process, known as biotin. In 1940 other scientists concluded that the biotin is the eighth in vitamin family - Vitamin H. until the biotin founded people have a more profound understanding of the harmful of eating raw eggs, and find out the reason. There is an anti-biotin factor in raw egg white. It is a glycoprotein, and can be combined closely with biotinylated loss of activity. Cooked eggs, avidin loses activity, without the ability to bind with biotin.

Biotin combined with the enzyme involved in the fixing of carbon dioxide in the body and carboxylation process, with the body of important metabolic processes such as pyruvate carboxylation transformed into oxaloacetate, acetyl coenzyme A hydroformylation as malonyl-coenzyme A and other sugar and fat metabolism. The main biochemical reactions. It is also a growth factor for some microorganisms, a very small amount (0.005 ¼g) can make the growth of the test bacteria. For example, Alternaria mold growth requires a very small amount of biotin.

Human need about 100 to 300 micrograms daily. Raw egg in a protein avidin and biotin, the combined biotin can not be absorbed by the digestive tract; causing animals lack of biotin, appears to loss of appetite, glossitis, dander, dermatitis, hair removal and so on. However, yet see cases of human biotin deficiency may be due to the addition to the food source, intestinal bacteria can also synthesize biotin. Biotin is a coenzyme for a variety of enzymes in the human body, involved in the body's metabolism of fatty acids and carbohydrates; promote protein synthesis; also involved in vitamin B12, folic acid, pantothenic acid metabolism; to promote urea synthesis and excretion.

Biotin is helpful for hair loss, not only can prevent hair unprovoked fall, but also can prevent young people gray hair, and he also can maintain skin health. Used as cosmetics material, can increase the speed of the blood circulation in the blood vessels of the skin, in the concentration range of 0.1% to 1.0%, it is easy to be mixed with the oil formulation. Skin care cream, the movement of liquid medicine, foot analgesic cream, shaving, shampoo can be used. Biotin in nature in a wide range of distribution and present, human and animal remains healthy indispensable this substance, but because it is widely distributed in the food, almost all foods are more or less containing biotin, in addition, the daily amount needed is less, so under normal circumstances, most people will not lack this vitamin.


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