How Does the Lupron Infertility Drug Work?

Mar 19
08:17

2010

Katy Anderson

Katy Anderson

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The lupron infertility drug,How Does the Lupron Infertility Drug Work? Articles also known as leuprolide acetate, is a synthetic compound, very similar chemically to GnRH or gonadotropin releasing hormone that causes production of a hormone usually produced by the brain’s hypothalamus. The GnRH hormone travels through the vascular system to make its way to the pituitary gland where it causes the secretion of the FSH or follicle stimulation hormone and the LH or luteinizing hormone. The follicle stimulation hormone causes growth of your ovarian follicles and the luteinizing hormone causes the occurrence of ovulation. Therefore, when the lupron infertitliy drug is combined with the LH and FSH hormones the ovaries are affected and estrogen levels will rise.

 The Lupron infertility drug is administered through a 2.8ml multi-dose subcutaneous injection. The Lupron infertility drug is most often used on patients that are undergoing the stimulation cycle treatment that is combined with fertility drug injections, such as REpronex, Pergonal, Follistim, Gonal-F, or Humegon. The Lupron infertility drug is extremely useful for endometriosis, because the endometrial tissue can’t survive without the production of the LH and FSH hormones.

 Lupron Infertitliy drug is administered in 2 different ways when using it with ART protocols:

 1.       The first method is using lupron as a down regulator, meaning it is used to regulate the female hormonal system. Under this method, the lupron infertility drug is administered for 7 days, twice a day, after you have already ovulated, but before you anticipate the ART cycle. When given continuous Lupron infertility drug doses, the pituitary gland eventually will become desensitized, which will stop the production of the FSH and LH hormones and your estrogen levels will drop. This repression will reverse once the Lupron infertility treatment ceases. Once the estrogen levels have been lowered, FSH daily injections will begin. The FSH will work to stimulate egg development within your ovarian follicles.

2.       The second way to use the Lupron fertility treatment is most commonly referred to as the “Garcia or Flare” protocol. This protocol requires Lupron to be administered one time daily beginning on the 2nd day of your cycle. Then the FSH is given 2 times daily on the 5th day of your cycle in order to take advantage of Lupron’s initial estrogen increase (Flare).

The dosages and protocols of these drugs can vary greatly, so your physician will have to custom tailor the proper treatment for your body’s specific needs.

You have to realize that when following an ART protocol you must time ovulation precisely. The ovulation will be triggered by the LH hormone that will be eventually be suppressed by the Lupron infertility drug. Therefore, ovulation isn’t able to occur unless the patient is also receiving the LH hormone while on Lupron.

There are a few side effects associated with the Lupron infertility drug that include sweating, mood alteration, flushing, tender breasts, dizziness, constipation, vaginal dryness, fatigue, headaches, and irritation at the site of injection. These side effects are only temporary and will subside when you stop taking the Lupron infertility drug.

If you are infertile and searching for a natural way to overcome the issues you uncovered through your infertility blood test, I would highly recommend checking out the article about the Sign of Infertility that suggests an incredible natural remedy that has allowed several infertile couples who were at the end of their rope to conceive.